Tag Archives: hazara

Afghan Dataset

Posted by on January 16, 2014 190 comments

A paper, Afghan Hindu Kush: Where Eurasian Sub-Continent Gene Flows Converge by Julie Di Cristofaro, Erwan Pennarun, Stéphane Mazières, Natalie M. Myres, Alice A. Lin, Shah Aga Temori, Mait Metspalu, Ene Metspalu, Michael Witzel, Roy J. King, Peter A. Underhill, Richard Villems, Jacques Chiaroni was published at PLoS One about the genetics of the people of Afghanistan.

Thanks to Mait Metspalu, the data is available online. It consists of:

  • 5 Hazara
  • 5 Pashtun
  • 5 Tajik
  • 4 Turkmen
  • 5 Uzbek

Here are the HarappaWorld Admixture results for the samples in this dataset.

You can check the spreadsheet too.

Tadjik1_44Af and Pashtun2_6Af seem to be outliers and there's a possibility they are mislabeled. I would like to look into these two samples further before I calculate group averages.

You can compare these Pashtun results to HGDP Pathan and HAP Pashtun results.

HGDP

Posted by on January 25, 2011 3 comments

Human Genome Diversity Project (HGDP) is the best resource for a diverse set of genomic data. It has 1050 individuals from 52 different populations.

I got the Stanford University data which has data for 660,918 SNPs from 1,043 samples. It is claimed that the forward strand is given but that turned out not to be true and I had to flip strands and make sure I didn't include any ambiguous A/T or C/G strands in my dataset.

I followed the recommendations of Rosenberg (spreadsheet) in excluding some atypical samples and relatives, leaving me with 940 samples.

I also excluded the Native American samples because we are not interested in them and they are very closely related either due to recent endogamy or ancient bottlenecks. (yeah I had the nerve to write that.)

Of the total of 876 samples, here are the numbers for our populations of interest:

Balochi 24
Brahui 25
Burusho 25
Hazara 22
Kalash 23
Makrani 25
Pathan 22
Sindhi 24
Total South Asians 190

These samples have about 541,560 SNPs in common with 23andme v2.